Difference between Live and Killed Vaccines

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Administrator
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Which one is better: Live or Killed Vaccine?



Live Vaccine
  • Live attenuated organisms or organisms of lower virulence are used as agent
  • Gives strong immune response
  • Booster immunization is not required
  • Adjuvant is not required
  • Cold chain is required
  • Less costly
  • Chance of reversal of virulence is there
Killed Vaccine
  • Killed organisms are used as agent
  • Gives relatively poor immune response
  • Booster immunization is required
  • Adjuvant is required
  • Cold chain is not required
  • Costly
  • No chance of reversal of virulence is there i.e. Safe
 
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